This project aims to better understand the factors that explain the distrust of Black communities in Canada towards vaccination against COVID-19. More so, it will help to understand how these factors evolve and change over time, depending on the evolution of the pandemic and the associated health measures as well as the vaccination promotion campaigns at the heart of this project. Participants in this research will be recruited from Ontario and Quebec, both vaccinated and unvaccinated; these two provinces include nearly 80% of black communities in Canada. They will provide information about their profile and whether or not they are vaccinated, their knowledge, beliefs and attitudes towards COVID-19 vaccines, experiences of discrimination and their mental health. Focus groups will also be held with vaccinated and unvaccinated participants, Black community leaders, and primary health care and public health professionals. The information collected will be analyzed and the results will make it possible to set up educational campaigns on the vaccine. These campaigns will reduce misconceptions or false beliefs about vaccines and increase confidence in the benefits of getting vaccinated against COVID-19. The programs and tools that have proven themselves through this project can be used in the future in other vaccination contexts with black communities in Canada and elsewhere in the West.